Constipation with bloating: a clinical approach to evaluation and management.
Constipation and bloating are common bothersome gastrointestinal (GI) symptoms that frequently occur concurrently. It is important to recognize the underlying condition(s) and tailor therapeutic interventions appropriately. This review discusses the evaluation and management of patients with constip…
Postmenopausal ovarian torsion with intratumoral gas and markedly elevated CA-125/CA 19-9: A case report.
Adnexal masses in postmenopausal women represent a significant clinical challenge. This case report describes the clinical presentation, diagnostic evaluation, and surgical management of a large adnexal mass complicated by ovarian torsion in a postmenopausal woman. A 65-year-old postmenopausal woman…
Tuberculous pyosalpinx associated with serous tubal intraepithelial lesion: a case report on evidence of early tubal neoplastic transformation.
Serous tubal intraepithelial lesion (STIL) is an uncommon precursor lesion in the spectrum of tubal serous neoplasia, characterised by atypical epithelial proliferation, aberrant p53 expression and a low proliferative index. Chronic inflammatory conditions such as tuberculosis may contribute to carc…
Transvaginal Ultrasonography for Detection of PID-Related Adhesions: A Case Report.
Diagnosis of acute and chronic pelvic inflammatory disease continues to be a challenge despite advances in investigative procedures. Complications of PID include infertility, chronic pelvic pain and ectopic pregnancy. Currently, transvaginal ultrasonography is primarily used to detect tubo-ovarian a…
Comprehensive multi-omics analyses elucidate the mechanism of male sexual dysfunction induced by chronic prostatitis/chronic pelvic pain syndrome in the experimental autoimmune prostatitis rat model.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), characterized by persistent pain, is significantly associated with sexual dysfunction, yet the underlying mechanisms remain poorly understood. This study sought to elucidate the underlying central mechanisms linking autoimmune prostatitis t…
Perception of prolapse-associated symptoms by age: a cross-sectional study.
We sought to determine if age affects how women with pelvic organ prolapse (POP) perceive associated symptoms. A secondary analysis was performed on a previously published cross-sectional study of participants presenting for POP to three urogynecology centers in the United States, the United Kingdom…
Endometriosis Unveiled: Innovations in Diagnosis and Management of Endometriosis.
Endometriosis is a chronic inflammatory condition that can result in chronic pain through complex nociceptive, neuropathic, and nociplastic pathways. This article provides a comprehensive background on endometriosis as well as future directions in diagnosis and management. The diagnosis of endometri…
The endometriosis-adenomyosis spectrum: shared pathophysiology and microenvironment-driven disease divergence.
Endometriosis and adenomyosis are common gynecologic disorders associated with dysmenorrhea, chronic pelvic pain, and infertility. Although they share several molecular features, the mechanisms by which endometrium-derived tissues develop distinct pathological phenotypes in different tissue environm…