Constipation with bloating: a clinical approach to evaluation and management.
Constipation and bloating are common bothersome gastrointestinal (GI) symptoms that frequently occur concurrently. It is important to recognize the underlying condition(s) and tailor therapeutic interventions appropriately. This review discusses the evaluation and management of patients with constip…
miR-145-5p in predicting caesarean section postoperative complications in scarred uterus cases: a prospective cohort study.
To investigate whether serum micro (miR)-145-5p for postoperative complications in patients with scarred uterus undergoing caesarean section, suggesting its potential as an adjunctive molecular biomarker for clinical preoperative risk assessment. A total of 198 women were divided into high-expressio…
Second stage labour duration and pelvic floor outcomes in primiparous women delivering macrosomic foetuses: a prospective study.
To investigate the association between the duration of the second stage of labour (SSL) and early postpartum pelvic floor dysfunction (PFD) in primiparous women delivering macrosomic foetuses. 200 eligible primiparous women were stratified by SSL duration into Group A (t ≥ 3h), Group B (2h ≤ t < 3h)…
Responsiveness, Smallest Detectable Change, and Minimal Important Change of the Turkish Pelvic Floor Distress Inventory-20 Following Pelvic Floor Muscle Training.
The Pelvic Floor Distress Inventory-20 (PFDI-20) is a widely recognized clinical tool designed to assess the severity of distress caused by pelvic floor symptoms. Within the context of conservative physiotherapy and pelvic floor rehabilitation, this study aimed to determine the responsiveness, small…
Obesity is a major public health challenge with substantial effects on women's health and quality of life. Pelvic organ prolapse (POP), characterized by the descent of pelvic organs into the vaginal canal, is influenced by both obesity-related mechanical forces and molecular alterations. This review…
Management of constipation: A narrative review of evolving strategies and methodological challenges.
Constipation is a common multifactorial gastrointestinal disorder with a significant impact on quality of life, healthcare utilization, and economic burden. It encompasses a spectrum of symptoms, including infrequent bowel movements (fewer than three per week), lumpy or hard stools (Bristol Stool Fo…
miR-1260b mediates rehabilitation of postpartum pelvic floor dysfunction by targeting PIN1.
Postpartum pelvic floor dysfunction (PFD) impairs women's quality of life with unmet needs in early diagnosis and treatment. This study explored the expression profile, diagnostic value, and molecular mechanism of miR-1260b in postpartum PFD. This study included 60 PFD cases and 60 healthy controls.…
Pelvic venous disorders and orthostatic intolerance: A systematic review of diagnostic associations and treatment outcomes.
Pelvic venous disorders (PeVD) are recognised causes of chronic pelvic pain; emerging evidence suggests that venous outflow obstruction or reflux can also provoke orthostatic intolerance (OI) by infra-diaphragmatic pooling and reduced preload. Diagnostic and therapeutic frameworks for this overlap r…