A functional gastrointestinal disorder causing chronic abdominal pain and altered bowel habits.
✦ AI summary
Here's what these sources say about IBS:
- **Symptom overlap and diagnosis**: IBS falls under "disorders of gut-brain interaction" (DGBI), a category being updated in newer diagnostic frameworks (Rome V), which includes conditions like functional bloating and functional diarrhea [3]. Self-reported "alarm" symptoms (like major changes in bowel habits) are common in the general population but even more frequent among people with DGBI conditions like IBS, so these symptoms need to be interpreted carefully rather than assumed to always signal something serious [2].
- **Gut microbiome connection**: Research is exploring whether gut bacteria imbalance ("dysbiosis") can be measured in a standardized way across different countries, with IBS included as one of the conditions studied in this context [1]. New drug-delivery approaches, like oral hydrogel systems, are also being explored as ways to target the gut microbiome more precisely for conditions including IBS [8].
- **Diet and IBS risk/management**: A large study following people over time found that eating patterns closer to the "planetary health diet" (an environmentally-focused eating pattern) were linked to lower rates of developing IBS, especially in women and people under
This is an AI-generated summary of the sources below — not medical advice. Always talk to a doctor or pharmacist about your own situation.
Towards standardized gut microbiota diagnostics: normobiosis beyond geographical borders.
Defining clinically meaningful reference states of the human gut microbiota remains a major barrier to the clinical translation of microbiome testing, largely due to variability across populations. We aimed at evaluating whether dysbiosis can be identified in a standardized, geography-independent ma…
Constipation with bloating: a clinical approach to evaluation and management.
Constipation and bloating are common bothersome gastrointestinal (GI) symptoms that frequently occur concurrently. It is important to recognize the underlying condition(s) and tailor therapeutic interventions appropriately. This review discusses the evaluation and management of patients with constip…
Global Prevalence of Self-Reported Alarm Features in the General Population and Among Individuals With Disorders of Gut-Brain Interaction-Results From the Rome Foundation Global Epidemiology Study.
Data on the global prevalence of alarm features in the general population and among individuals with disorders of gut-brain interaction (DGBI) are limited. We analysed data from the Rome Foundation Global Epidemiology Study to estimate the prevalence of fourteen self-reported alarm features in the g…
Thoracic outlet syndrome in patients with clavicle fracture: Case report and national analysis.
Thoracic outlet syndrome (TOS) is a neurovascular condition caused by compression of the brachial plexus or subclavian vessels as they pass through the thoracic outlet. Since the clavicle border the thoracic outlet, injury to the clavicle and potentially post-traumatic callus formation, malunion, or…
Early Prediction of Diabetic Macular Edema via Machine Learning Survival Analysis on Checkup Data.
To predict the risk of diabetic macular edema (DME) onset and to identify features of the risk subgroups. Population-based observational study with a case-control design. Health checkup and diagnosis data from the JMDC claims database (January 2005-July 2020), one of the largest Japanese epidemiolog…
Gastric myoelectrical activity and autonomic dysfunction in children with IBD and IBS: An electrogastrographic and autonomic correlation study.
Sixty-two children (18 with inflammatory bowel disease [IBD], 28 with irritable bowel syndrome [IBS], 18 healthy controls) underwent pre- and postprandial electrogastrography and autonomic assessment with the Composite Autonomic Symptom Score-31 (COMPASS-31) and Composite Autonomic Severity Scale (C…
Oral hydrogel systems in lower gastrointestinal disorders: From disease-based therapy to microbiota-guided design.
The lower gastrointestinal tract is a complex ecological system involved in epithelial barrier maintenance, immune regulation, microbial metabolism, and host homeostasis. Disruption of this environment is closely associated with lower gastrointestinal disorders, including inflammatory bowel disease…
Impact of 3-day turmeric supplementation on fasting and postprandial LPS and chylomicron-related markers in patients with IBS: A randomized crossover trial.
Lipopolysaccharide (LPS) has been implicated in increased gut permeability and low-grade mucosal inflammation, conditions that are linked to the pathophysiology of irritable bowel syndrome (IBS). Because increased dietary fat intake can both trigger IBS symptoms and promote LPS translocation in the…