An autoimmune reaction to gluten that damages the small intestine lining, causing malabsorption.
✦ AI summary
Based on these sources, the research touches on Coeliac Disease in a few different contexts, but none of them are dedicated deep-dives into the condition itself:
- **A food additive link**: Microbial transglutaminase (mTG), an enzyme used in food processing, has been flagged as possibly triggering celiac disease by creating "non-self" protein structures that the immune system reacts to; researchers suggest food safety authorities should reconsider its regulatory status [5]. A related sensor-development study also notes that MTGase-treated wheat products can provoke immune reactivity that may contribute to celiac disease [2].
- **Autoimmune disease mechanisms**: Coeliac disease is mentioned as one example within a broader discussion of how proteins get chemically altered in the body (a process called posttranslational modification), which may help explain why certain autoimmune diseases, including celiac disease, develop [4].
- **Malnutrition connection**: A hospital study found that a notable proportion of children with severe acute malnutrition also had undiagnosed coeliac disease, and that a particular genetic marker (HLA-DQ2.5) was more common in these children, suggesting coeliac disease should be considered as an underlying cause in some maln
This is an AI-generated summary of the sources below — not medical advice. Always talk to a doctor or pharmacist about your own situation.
GI symptomsFatigueBloatingDiarrhoeaAnaemiaBrain fog
Stepwise management of median arcuate ligament syndrome with visceral artery aneurysm: Surgical ligament release followed by percutaneous transluminal angioplasty.
A woman in her 20s presented with an 8-year history of postprandial abdominal pain. Contrast-enhanced computed tomography revealed severe stenosis at the origin of the celiac artery, collateral circulation from the superior mesenteric artery, and an associated inferior pancreaticoduodenal artery ane…
A dual-mode electrochemical-colorimetric aptasensor based on HCR-CRISPR/Cas12a cascade amplification for MTGase detection.
Microbial transglutaminase (MTGase) is widely used in food processing, but its potential food safety risks cannot be neglected. MTGase-treated wheat products show immunoreactivity, which may induce celiac disease and damage intestinal barrier function. Therefore, trace detection of MTGase is of grea…
Celiac Disease and HLADQ2/DQ8 Genotypes in Severe Acute Malnutrition: A Hospital-Based Study.
To determine the proportion of celiac disease (CD) among children with severe acute malnutrition (SAM) and to evaluate the distribution and association of HLA-DQ2/DQ8 genotypes in affected children. Children aged 6-59 months diagnosed with SAM were assessed for inclusion. Those with secondary causes…
Embolization of spontaneous retroperitoneal bleeding fed by aneurysmal arc of Bühler: Case report and technical considerations.
The arc of Bühler (AOB) is a rare embryonic anastomosis between the celiac artery and the superior mesenteric artery, which may become a crucial collateral pathway in cases of celiac axis stenosis. We report a challenging case of a 70-year-old woman presenting with hemorrhagic shock owing to a bleed…
The food additive microbial transglutaminase is a potential new environmental inducer of autoimmune diseases.
Microbial transglutaminase (mTG) is a frequently used processed food additive, and the consumption of its cross-linked complexes is rapidly expanding. Despite numerous reports concerning its public safety, it is designated as a processing aid and classified as safe for use. mTG and/or its cross-link…
Outcomes of pediatric median arcuate ligament release: A single-center experience.
Median arcuate ligament syndrome (MALS) is a rare condition caused by compression of the celiac artery by the median arcuate ligament. The surgical treatment for MALS is a median arcuate ligament release (MALR). While outcomes of MALR are well described in adults, pediatric data remain limited. Leve…
Median Arcuate Ligament Compressing Multiple Arteries in a Young Man Treated by Surgical Release.
Background: Asymptomatic compression of celiac artery (CA) by median arcuate ligament (MAL) is quite common, but simultaneous compression of other arteries by MAL is very rare. Case details: A 20-year-old man presented with post-prandial epigastric pain for the past 1 year and a 5 kg weight loss. On…
Rhinosinusitis in Adults With Autoimmune Diseases: A Scoping Review.
Chronic rhinosinusitis (CRS) and autoimmune diseases share inflammatory pathways, yet the scope of their association across diverse autoimmune conditions remains incompletely characterized. This scoping review aimed to map the breadth of evidence examining relationships between autoimmune diseases a…