Myositis

185 papers & discussions

An inflammatory muscle disease causing progressive muscle weakness and inflammation.

Muscle weaknessMuscle painFatigueDifficulty swallowingSkin rashJoint pain

Research

185
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PubMed

Proliferative myositis of the biceps brachii: A sarcoma mimicker.

Proliferative myositis is a rare benign intramuscular inflammatory pseudotumor that may clinically mimic a soft tissue sarcoma due to its rapid growth and painful presentation. We report the case of a 50-year-old man presenting with a rapidly enlarging, firm, and painful mass of the left arm, which…

myositis
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PubMed

A pilot study to evaluate the efficacy of an at-home TheraPutty® hand exercise intervention on strength and function in adults with inclusion body myositis.

Inclusion body myositis (IBM) is the most common idiopathic inflammatory myopathy after age 50, causing progressive weakness of quadriceps and finger flexors. With no effective disease-modifying therapies, accessible non-pharmacological strategies are needed. Exercise is safe, may slow disease progr…

myositislichen sclerosus
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PubMed

fAI-BRO: a multimodal AI decision-support system to address diagnostic delay in fibromyalgia syndrome.

To evaluate the diagnostic accuracy and patient acceptability of fAI-BRO (Fibromyalgia AI-Based Rheumatology Observer), a multimodal artificial intelligence (AI) system integrating video-based visual descriptor analysis and psycholinguistic transcript evaluation, for distinguishing fibromyalgia synd…

fibromyalgialupusrams
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PubMed

A patient-derived benchmark for evaluating large language models in connective tissue diseases: blinded multi-stakeholder assessment and guideline comparison.

To co-develop disease-specific patient questions for connective tissue diseases (CTDs), compare patient/rheumatologist ratings of answers from language models (LLMs) versus Google Search, and quantify EULAR coverage of these patient-prioritized questions. In this prospective single-center observatio…

lupusmsmyositislichen sclerosus
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PubMed

Bladder carcinoma associated with anti-NXP2-positive inflammatory myopathy: a case-based review.

Anti-nuclear matrix protein 2 (NXP2) antibodies are increasingly recognized in adult idiopathic inflammatory myopathies (IIM) and have been associated with an elevated risk of malignancy. However, the spectrum of associated malignancies remains incompletely characterized. We report a case of anti-NX…

msmyositis
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PubMed

Single-Dose Nivolumab as a Trigger of Myocarditis, Myositis, and Myasthenia Gravis Overlap Syndrome With Late Cardiac Death Despite Initial Recovery: A Case Report.

BACKGROUND Immune checkpoint inhibitors (ICIs) have transformed the treatment of advanced malignancies but can cause life-threatening immune-related adverse events. Myocarditis, myositis, and myasthenia gravis (MMM) overlap syndrome is a rare, highly morbid complication with high mortality. Most cas…

myositismixed connective tissuemyasthenia gravisthoracic outlet syndrome
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PubMed

Rhabdomyolysis After COVID-19.

We report a case of a kidney transplant recipient who presented with generalised muscle pain, weakness and brown urine discoloration in the setting of acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Investigations demonstrated rhabdomyolysis with elevated creatine kinas…

myositislichen sclerosushereditary angioedema
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PubMed

Rapid efficacy of anifrolumab in refractory cutaneous dermatomyositis.

myositis
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