A vascular condition where the right iliac artery compresses the left iliac vein, increasing DVT risk.
✦ AI summary
May-Thurner Syndrome (MTS) is a condition where the left common iliac vein gets compressed, usually by a nearby artery, which can slow blood flow in the left leg and raise the risk of blood clots (deep vein thrombosis) and long-term venous insufficiency [7]. It's thought to be underdiagnosed and mostly affects younger to middle-aged women, with pregnancy and hormone therapy mentioned as possible risk factors [7]. Research also notes that people with connective tissue conditions like hypermobile Ehlers-Danlos syndrome or hypermobility spectrum disorder show significantly higher rates of this vein compression than people without these conditions [9], and MTS has been described as a contributing cause in unusual situations like recurrent clotting in a transplanted kidney [6]. For diagnosis, imaging tools such as ultrasound, CT/MR venography, and specialized angiography (with newer 3D techniques reportedly more accurate than older 2D methods) are used [2][7], though some sources caution that imaging findings of vein compression alone can be present in people without symptoms, and labeling this as a "syndrome" based on imaging alone may lead to unnecessary tests or procedures [
This is an AI-generated summary of the sources below — not medical advice. Always talk to a doctor or pharmacist about your own situation.
Left leg swellingPelvic painDVT riskLeg heavinessFatigueVaricose veins
A case of right lower limb Clinical Etiological Anatomical Pathophysiological C6 chronic venous insufficiency accompanied by left iliac vein compression syndrome.
This case report describes treatment of right limb Clinical Etiological Anatomical Pathophysiological class C6 chronic venous insufficiency with left iliac vein compression syndrome. The treatment strategy combined left iliac vein balloon angioplasty with right great saphenous vein endovenous laser…
Microsurgical Varicocelectomy with Spermatic Vein to Superficial Epigastric Vein Bypass in Adolescents.
A microsurgical venous bypass between the internal spermatic vein (ISV) and inferior epigastric vein was proposed five decades ago for varicocele treatment. Limitations of this technique include a large incision, transverse fascia transection, delayed recovery, and mandatory venography to rule out e…
Effectiveness of 2D-DSA and 3D-DSA in the Evaluation of Iliac Vein Stenosis: A Multicenter Prospective Study.
To compare the sensitivity of measuring iliac vein stenosis using two-dimensional digital subtraction angiography (2D-DSA) and three-dimensional digital subtraction angiography (3D-DSA), with multidetector computed tomography venography (MDCTV) as the reference standard. Between January 2020 and Jan…
Endovascular management of symptomatic May-Thurner syndrome: real-world procedural approaches and outcomes.
May-Thurner syndrome (MTS) is characterized by extrinsic venous compression by the arterial system in ilio-caval territory leading to venous stasis, a predisposition to deep vein thrombosis (DVT), and edema. Endovascular interventions have become the cornerstone of treatment for patients with sympto…
Compression and Superficial Varicosities Outperform Gonadal Vein Diameter in Differentiating Symptomatic from Asymptomatic Pelvic Venous Disorders: A Case-Control Study.
To assess whether gonadal vein (GV) diameter associates with pelvic venous disorder (PeVD)-consistent symptoms in women with pelvic varices, compared with proximal venous outflow obstruction (VOO; iliac/left renal vein stenosis/obstruction) and superficial varicosities. This retrospective, case-cont…
Anticoagulation Management and Recurrent Thrombosis after Venous Stenting for Deep Vein Thrombosis and Post-thrombotic Syndrome.
There are no evidence based recommendations for anticoagulation management after venous procedures. This study aimed to evaluate how anticoagulation was managed after venous stenting for deep vein thrombosis (DVT) and post-thrombotic syndrome (PTS). Patients who underwent venous stenting for DVT or…
Comparative assessment of left common iliac vein compression in patients with hypermobile Ehlers-Danlos syndrome, hypermobility spectrum disorder and healthy controls - A retrospective single-centre study.
ObjectivesHeritable connective tissue disorders (HCTDs), including hypermobile Ehlers-Danlos syndrome (hEDS) and hypermobile spectrum disorder (HSD), have complex clinical manifestations, but the prevalence of left common iliac vein (LCIV) compression in these groups is not well known. This study ai…
Clinical manifestations, diagnosis, and therapeutic advances in May-Thurner Syndrome: A comprehensive literature review.
May-Thurner Syndrome (MTS), or iliac vein compression syndrome, is an underdiagnosed vascular condition where the left common iliac vein is compressed, typically by the right common iliac artery. This impairs venous outflow from the left lower extremity, leading to manifestations ranging from chroni…