The effectiveness of wrist-ankle acupuncture on post-stroke shoulder-hand syndrome: A systematic review and meta-analysis.
Shoulder-hand syndrome is one of the most common post-stroke complications. It presents with a variety of symptoms, especially pain and a limited range of motion of the wrist and hand, which negatively affect an individual's quality of life and ability to complete daily tasks. Nurse-led complementar…
Mesotherapy With Lidocaine and Ketamine in Complex Regional Pain Syndrome Type 1: A Randomized Double-Blind Trial.
Complex regional pain syndrome type 1 (CRPS1) is a disabling pain syndrome whose treatment remains challenging. Mesotherapy is a therapeutic method involving the injection of low doses of active substances through the skin. No studies assessed mesotherapy in CRPS1 patients. The aim of this study was…
Inhibition of Janus kinase/signal transducer and activator of transcription reduces nociceptive sensitization in a murine model of complex regional pain syndrome.
Complex regional pain syndrome (CRPS) is a disabling condition relying in part on the production of pain-supporting autoantibodies. The Janus kinase/signal transducer and activator of transcription (JAK-STAT) signaling system regulates the adaptive system of immunity and is targeted to control autoi…
A Review of Physiological Measurements Among Patients Diagnosed With Complex Regional Pain Syndrome.
The combination of disproportionate pain intensity and limb disuse is often diagnosed as complex regional pain syndrome (CRPS), a label that may imply a specific measurable pathophysiology. In a review of studies of pathophysiology associated with diagnosis of CRPS, we asked, "How often are studies…
Sleep Disturbances in Patients with Complex Regional Pain Syndrome: A Pilot Exploratory Study on Pain Characteristics, Functional Impairment, and Psychological Factors.
Our aim was to evaluate sleep quality and excessive daytime sleepiness in complex regional pain syndrome (CRPS) and explore their associations with pain characteristics, functional impairment, depressive symptoms, and pain coping strategies. This pilot exploratory, cross-sectional observational stud…
Gabapentinoids for Neuropathic Pain Management: A Systematic Umbrella Review.
This umbrella review aimed to evaluate the effectiveness of gabapentinoids, including dosing and risk profile, for the management of neuropathic pain. Eligibility criteria were restricted exclusively to systematic reviews and meta-analyses conducted under PRISMA reporting standards. Methodological q…
Invasive Spinal Neuromodulation for Chronic Pain in Pediatric Patients: A Scoping Review.
Chronic pain affects up to 21% of pediatric patients and significantly impairs function and quality of life. Although spinal neuromodulation, including spinal cord stimulation (SCS) and dorsal root ganglion stimulation (DRG-S), has demonstrated efficacy in adults, evidence in children remains limite…