Compression of nerves or blood vessels between the collarbone and first rib, causing arm pain and numbness.
✦ AI summary
Thoracic outlet syndrome (TOS) involves compression of nerves or blood vessels where they pass near the collarbone and first rib, and sources describe three types—nerve-related, vein-related, and artery-related—each with different causes and symptoms [3]. The artery-related form is described as rare but potentially serious, sometimes linked to an extra "cervical rib" that presses on the artery, leading to pain, tingling, color changes in the arm, and in one case, blood clot and reduced blood flow requiring surgery to remove the rib and repair the artery [1]. A case report describes TOS developing months after a collarbone fracture, with a related larger database analysis finding it happens more often in adults aged 40–64, especially after fractures treated with surgical fixation, and that things like obesity, smoking, blood-clotting tendencies, and extra cervical ribs may raise the risk [5]. One preliminary study looked at whether birth-related injuries (like shoulder dystocia or forceps delivery) might be tied to later development of nerve-related TOS, finding a higher-than-expected rate of reported birth trauma in a small group of surgically treated TOS patients, though the researchers call this an early pilot finding needing more study [3]
This is an AI-generated summary of the sources below — not medical advice. Always talk to a doctor or pharmacist about your own situation.
Arm painNumbness in fingersWeaknessCold handsNeck painShoulder pain
From compression to denervation: Multimodality imaging of cervical rib-related arterial thoracic outlet syndrome.
Thoracic outlet syndrome (TOS) encompasses a spectrum of disorders caused by compression of neurovascular structures at the thoracic outlet. Arterial thoracic outlet syndrome (aTOS) is rare, accounting for less than 1% of cases, yet carries significant morbidity due to arterial injury, thrombosis, a…
Surgical outcomes following spinal fusion for cervical versus noncervical fractures in ankylosing spondylitis and DISH.
Ankylosing spondylitis (AS) and diffuse idiopathic skeletal hyperostosis (DISH) are 2 distinct spondyloarthropathies characterized by progressive spinal ankylosis. Despite their differing pathophysiologies, both conditions create long rigid spinal segments that are vulnerable to unstable fractures.…
Birth Trauma and Thoracic Outlet Syndrome: Preliminary Evidence.
Thoracic outlet syndrome (TOS) arises from compression of neurovascular structures as they traverse the thoracic outlet at the base of the neck, with 3 main types: neurogenic, venous, and arterial. Established risk factors include acute trauma, repetitive upper extremity use, or congenital anatomica…
Thoracic outlet syndrome in patients with clavicle fracture: Case report and national analysis.
Thoracic outlet syndrome (TOS) is a neurovascular condition caused by compression of the brachial plexus or subclavian vessels as they pass through the thoracic outlet. Since the clavicle border the thoracic outlet, injury to the clavicle and potentially post-traumatic callus formation, malunion, or…
Cardiovascular risk goal attainment in the United States rheumatologic population.
Rheumatologic diseases are independently linked to premature cardiovascular (CV) events. The emerging field of cardio-rheumatology addresses the intersection of inflammation and accelerated atherosclerosis driving excess CV risk. Despite calls to action, data on risk factor optimization, antihyperli…
OGN inhibits apoptosis and ferroptosis via FSHR in human granulosa cells: implications for polycystic ovary syndrome.
Background Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by granulosa cell dysfunction, including impaired proliferation, excessive apoptosis, and ferroptosis, which contribute to abnormal follicular development and ovarian dysfunction. This study aims to investigate…
Stimulating Thyrotropin Receptor Antibodies Enhance the Expression of Both Thyrotropin Receptors and Insulin-Like Growth Factor 1 Receptors in Fibroblasts.
Thyrotropin (TSH) and insulin-like growth factor 1 (IGF-1) signals have been shown to be additive in their action on thyroid cells and fibroblasts, and this coordination emphasizes the role of TSH receptor (TSHR) and IGF-1 receptor (IGF-1R) signaling exerted by stimulating TSHR antibodies in patient…
Mild Thyroid Eye Disease-The Most Common yet the Least Studied Presentation of Thyroid Eye Disease.
Mild thyroid eye disease (TED) is the most common form of TED, yet it is the least studied. Uncertainties about the natural history and prevention, and underfunding for clinical research, are an obstacle to improving the management of this important group of patients. The available evidence suggests…