A tick-borne bacterial infection that, when inadequately treated, can cause chronic musculoskeletal and neurological symptoms.
✦ AI summary
Here's what these sources cover on Lyme disease:
**Diagnosis and symptoms:** Recognizing skin rashes tied to tick-borne illnesses is described as important in emergency settings, since early diagnosis may help reduce chronic complications later on [1]. In one case report, an older man developed severe cognitive decline linked to disseminated Lyme disease occurring together with babesiosis (another tick-borne infection), and the source notes that older adults may face delayed diagnosis and more severe complications from these infections [9]. Another study on children with facial palsy found that those whose palsy was linked to Lyme disease actually had better recovery rates than those with palsy of unknown cause, though some in both groups reported lasting mental health effects [7].
**Long-term/persistent symptoms:** One review discusses "post-treatment Lyme disease syndrome" (PTLDS) alongside conditions like long COVID and ME/CFS, noting shared symptoms such as fatigue and cognitive difficulties, and suggesting these may involve immune system dysregulation in some patients. It reviews immune-based treatments studied in these conditions but stresses that evidence for benefit is strongest only in patients with specific identifiable immune ab
This is an AI-generated summary of the sources below — not medical advice. Always talk to a doctor or pharmacist about your own situation.
Recognition of Cutaneous Symptoms of Common Tick-Borne Illness in the Emergency Department.
Tick-borne diseases occur throughout the United States, with a disease burden that ranges from mild to severe. As temperatures rise with climate change, the active season for ticks increases, and more tick-borne illness is seen (Centers for Disease Control and Prevention, 2022a). Many patients prese…
Tick-borne pathogens in dogs and their ticks in France: Molecular and serological evidence from a multicenter participatory study.
Canine tick-borne diseases (TBDs) are expanding globally, representing an increasing concern for both veterinary and public health. Dogs, due to their close contact with humans and frequent exposure to ticks, may serve as valuable sentinels for zoonotic risk. Between December 2022 and December 2023,…
Molecular detection of Borrelia burgdorferi sensu lato in questing ticks: One year of sampling in Bologna (Northern Italy).
Borrelia burgdorferi sensu lato (s.l.) includes several genospecies responsible for Lyme borreliosis (LB), a major zoonotic disease transmitted by Ixodes spp. ticks. In Western Europe, LB incidence has risen in recent decades, with documented expansion into previously non-endemic regions. A cross-se…
Photopolymerizable placenta-derived ECM hydrogel enhances hUC-MSC-mediated wound healing via coordinated immunomodulation and angiogenesis.
Mesenchymal stromal/stem cells (MSCs) hold great promise for regenerative medicine due to their potent immunomodulatory properties and favorable safety profile. However, their low survival, poor retention, and limited engraftment in injured tissues remain major barriers to clinical efficacy. Here, w…
Stimulating Thyrotropin Receptor Antibodies Enhance the Expression of Both Thyrotropin Receptors and Insulin-Like Growth Factor 1 Receptors in Fibroblasts.
Thyrotropin (TSH) and insulin-like growth factor 1 (IGF-1) signals have been shown to be additive in their action on thyroid cells and fibroblasts, and this coordination emphasizes the role of TSH receptor (TSHR) and IGF-1 receptor (IGF-1R) signaling exerted by stimulating TSHR antibodies in patient…
Therapeutic plasma exchange and immunomodulatory strategies in post-infectious syndromes: A review of immune dysregulation in PTLDS, long COVID, ME/CFS, and PANS/PANDAS.
Post-infectious syndromes including post-treatment Lyme disease syndrome (PTLDS), long COVID, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), and pediatric acute-onset neuropsychiatric syndrome (PANS)/pediatric autoimmune neuropsychiatric disorders associated with streptococcal infectio…
Interfacial Characteristics of a Fly Ash-Based Artificial Aggregate.
A fly ash-based artificial aggregate with a compressive strength of >60 MPa was prepared via cement activation and alkali activation using >75% fly ash as the principal raw material. The mechanical properties of concrete prepared using this aggregate and the characteristics of the interfacial transi…
Neuroborreliosis in children: Focus on ischemic stroke-a case report and literature review.
Lyme borreliosis-the most prevalent tick-borne disease in the United States, Canada and Europe-is a systemic infection caused by the spirochete Borrelia burgdorferi that can spread to the nervous system, where it may manifest as neuroborreliosis with potentially severe complications. Despite a world…